Wives with Knives features gripping stories of women who have committed violent crimes against their husbands or lovers. Some women endured years of emotional, sexual, and physical abuse before fighting back. Others were motivated by greed and jealousy.

Each episode features two compelling stories of women who have fought at close range. Using first-hand accounts from the actual women who committed the crimes, as well as police, investigators, family members, and the victims themselves, each episode of Wives with Knives reveals the traumatic events that led up to these deadly confrontations.